Pulmonary & Critical Care Fellowship Program
MGH BIDMC Harvard Medical School

Ari Moskowitz, MD

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Ari Moskowitz, MD

Instructor in Medicine

 

 

 

 

 

Academic Interests

Dr. Moskowitz is a clinical researcher interested in avenues for improving the care of patients during the acute phase of critical illness. Ari is a faculty member of the Center for Resuscitation Science at BIDMC and is leading, along with Dr. Michael Donnino, a number of clinical trials in sepsis and cardiac arrest. Dr. Moskowitz is particularly focused on mitochondrial dysfunction as a common denominator of organ injury in shock states and is exploring methods for improving mitochondrial function critical illness. 

Awards and Recognition
Dr. Moskowitz recently received a K23 award to study the effects of thiamine on renal function during sepsis. He additionally serves as a member of the American Heart Association Get With The Guidelines research task force.

 

A full list of Dr. Moskowitz’s published work can be found on My Bibliography.

More information can be found on Dr. Moskowitz's Harvard Catalyst profile

 

+Current Projects

  • A randomized trial of neuromuscular blockade following cardiac arrest
  • The Ascorbic acid, Corticosteroids, and Thiamin in Sepsis (ACTS) trial
  • Failure to Rescue in the Intensive Care Unit: A Multi-Disciplinary Approach to Reducing Preventable Cardiac Arrest

+Selected Publications

  • Moskowitz A, Grossestreuer AV, Berg KM, Patel PV, Ganley S, Casasola Medrano M, Cocchi MN, Donnino MW; Center for Resuscitation Science. The association between tidal volume and neurological outcome following in-hospital cardiac arrest. Resuscitation. 2017 Dec 29;124:106-111
  • Holmberg MJ, Moskowitz A, Raymond TT, Berg RA, Nadkarni VM, Topjian AA, Grossestreuer AV, Donnino MW, Andersen LW; American Heart Association’s Get With The Guidelines-Resuscitation Investigators. Derivation and Internal Validation of a Mortality Prediction Tool for Initial Survivors of Pediatric In-Hospital Cardiac Arrest. Pediatr Crit Care Med. 2017 Dec 12.
  • Holmberg MJ, Moskowitz A, Patel PV, Grossestreuer AV, Uber A, Stankovic N, Andersen LW, Donnino MW. Thiamine in septic shock patients with alcohol use disorders: An observational pilot study. J Crit Care. 2018 Feb;43:61-64
  • Moskowitz A, Patel PV, Grossestreuer AV, Chase M, Shapiro NI, Berg K, Cocchi MN, Holmberg MJ, Donnino MW; Center for Resuscitation Science. Quick Sequential Organ Failure Assessment and Systemic Inflammatory Response Syndrome Criteria as Predictors of Critical Care Intervention Among Patients With Suspected Infection. Crit Care Med. 2017 Nov;45(11):1813-1819
  • Moskowitz A, Chen KP, Cooper AZ, Chahin A, Ghassemi MM, Celi LA. Management of Atrial Fibrillation with Rapid Ventricular Response in the Intensive Care Unit: A Secondary Analysis of Electronic Health Record Data. Shock. 2017 Mar 21
  • Moskowitz A, Andersen LW, Karlsson M, Grossestreuer AV, Chase M, Cocchi MN, Berg K, Donnino MW; American Heart Association’s Get With the Guidelines-Resuscitation Investigators.. Predicting in-hospital mortality for initial survivors of acute respiratory compromise (ARC) events: Development and validation of the ARC Score. Resuscitation. 2017 Mar 4;115:5-10
  • Grossestreuer AV, Gaieski DF, Abella BS, Wiebe DJ, Moskowitz A, Ikeda DJ, Haukoos JS, Perman SM. Factors associated with post-arrest withdrawal of life-sustaining therapy. Resuscitation. 2017 Jan;110:114-119
  • Moskowitz A, Omar Y, Chase M, Lokhandwala S, Patel P, Andersen LW, Cocchi MN, Donnino MW. Reasons for death in patients with sepsis and septic shock. J Crit Care. 2016 Dec 2;38:284-288.
  • Moskowitz A, Andersen LW, Cocchi MN, Karlsson M, Patel PV, Donnino MW. Thiamine as a Renal Protective Agent in Septic Shock: A Secondary Analysis of a Randomized, Double-Blind, Placebo-Controlled Trial. Ann Am Thorac Soc. 2017 Feb 16
  • Donnino MW, Andersen LW, Chase M, Berg KM, Tidswell M, Giberson T, Wolfe R, Moskowitz A, Smithline H, Ngo L, Cocchi MN; Center for Resuscitation Science Research Group. Randomized, Double-Blind, Placebo-Controlled Trial of Thiamine as a Metabolic Resuscitator in Septic Shock: A Pilot Study. Crit Care Med. 2016 Feb;44(2):360-7
  • Andersen LW, Kim WY, Chase M, Berg K, Mortensen SJ, Moskowitz A, Novack V, Cocchi MN, Donnino MW; American Heart Association's Get With the Guidelines(®) – Resuscitation Investigators. The prevalence and significance of abnormal vital signs prior to in-hospital cardiac arrest. Resuscitation. 2015 Sep 9
  • Lokhandwala S, Moskowitz A, Lawniczak R, Giberson T, Cocchi MN, Donnino MW. Disease heterogeneity and risk stratification in sepsis-related occult hypoperfusion: A retrospective cohort study. J Crit Care. 2015 Jun;30(3):531-6
  • McSparron JI, Ricotta DN, Moskowitz A, Volpicelli FM, Roberts DH, Schwartzstein RM, Huang GC. The PrOSTE: identifying key components of effective procedural teaching. Ann Am Thorac Soc. 2015 Feb;12(2):230-4
  • Chan YF, Katz M, Moskowitz A, Levine S, Richardson L, Tuhrim S, Chason K, Barsan-Silverman K, Singhal A. Supplemental Oxygen to Suspected Stroke Patients in Pre-Hospital and Emergency Department Settings. Medical Gas Research. 2014 Oct: 4:16
  • Moskowitz A, Lee J, Donnino MW, Mark R, Celi LA, Danziger J. The Association Between Admission Magnesium Concentrations and Lactic Acidosis in Critical Illness. J Intensive Care Med. 2014 Apr 14
  • Moskowitz A, Graver A, Giberson T, Berg K, Liu X, Uber A, Gautam S, Donnino MW. The relationship between lactate and thiamine levels in patients with diabetic ketoacidosis. J Crit Care. 2014 Feb;29(1):182.e5-8
  • Moskowitz A, Chan YF, Bruns J, Levine SR. Emergency Physician and Stroke Specialist Beliefs and Expectations Regarding Telestroke. Stroke. 2010. 41: 805-809.