Pulmonary & Critical Care Fellowship Program
MGH BIDMC Harvard Medical School

Andrew J. Synn, MD


Andrew J. Synn, MD

Instructor in Medicine

Areas of Expertise: Investigation

Academic Interests

Dr. Synn is an investigator in the Institute for Lung Health at BIDMC. His research focuses on the use of advanced thoracic imaging techniques to study abnormal changes in the pulmonary blood vessels, with the goal of non-invasively identifying early pulmonary vascular disease in at-risk individuals.

Awards and Recognition

Morton M. Ziskind Clinical Research Scholar Award, American Thoracic Society

Outstanding Fellow/Trainee Award, Harvard Chan Program in Cardiovascular Epidemiology

Catalyst Award, American Lung Association

National Research Service Award, NHLBI/NIH

Harvard Catalyst Clinical/Translational Research Academy

Harvard Medical School Presidential Scholars Program Public Service Initiative Award

A full list of Dr. Synn’s published work can be found on My Bibliography.

More information can be found on Dr. Synn’s Harvard Catalyst Profile.

+Current Projects

  • Associations of vascular pruning on CT imaging with lung health, right heart function, and mortality
  • Clinical applications of CT vascular image analysis in individuals with COPD
  • Validation of CT vascular biomarkers against histologic vascular remodeling

+Selected Publications

  1. Synn AJ, Li W, San José Estépar R, Zhang C, Washko GR, O'Connor GT, Araki T, Hatabu H, Bankier AA, Mittleman MA, Rice MB. Radiographic Pulmonary Vessel Volume, Lung Function, and Airways Disease in the Framingham Heart Study. Eur Respir J. 2019 Jul 04. PMID: 31248956.
  2. Synn AJ, Zhang C, Washko GR, Estépar RSJ, O'Connor GT, Li W, Mittleman MA, Rice MB. Cigarette Smoke Exposure and Radiographic Pulmonary Vascular Morphology in the Framingham Heart Study. Ann Am Thorac Soc. 2019 Jun; 16(6):698-706. PMID: 30714821.
  3. Synn A, Rice MB. Is Bucolic Life Bad for Chronic Obstructive Pulmonary Disease? Ann Am Thorac Soc. 2018 Jul; 15(7):799-800. PMID: 29957034.
  4. Synn AJ, Makhni EC, Makhni MC, Rozental TD, Day CS. Distal radius fractures in older patients: is anatomic reduction necessary? Clin Orthop Relat Res. 2009 Jun; 467(6):1612-20. PMID: 19082864.