Pulmonary & Critical Care Fellowship Program
MGH BIDMC Harvard Medical School

Rod Rahimi, MD, PhD

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Rod Rahimi, MD, PhD

Instructor in Medicine

Areas of Expertise: Investigation

Academic Interests

Dr. Rahimi’s research focuses on defining the mechanisms regulating the development, maintenance, and function of memory CD4+ T cells in immune-mediated pulmonary diseases. Specifically, he utilizes both animal models and human subjects to investigate the biology of tissue-resident and re-circulating memory CD4+ T cells in allergic/eosinophilic asthma. Dr. Rahimi’s laboratory is affiliated with the Division of Pulmonary and Critical Care Medicine and the Center for Immunology and Inflammatory Diseases at MGH.

Awards and Recognition

Dr. Rahimi is the recipient of the Harvard Medical School Fellow Teaching Award in 2014. He received a Mentored Career Development Award (K08) via the NHLBI in 2017. He is the Editor of the Allergy, Immunology, and Inflammation Webinar Journal Club series for the American Thoracic Society. He is a member of the Allergy, Immunology, and Inflammation Program Committee for the American Thoracic Society

A full list of Dr. Rahimi’s published work can be found on My Bibliography.

More information can be found on Dr. Rahimi’s Harvard Catalyst Profile.

+Current Projects

  • Defining the mechanisms whereby tissue-resident memory CD4+ T cells survey for aeroallergen in peribronchial immune niches
  • Defining the mechanisms regulating effector Th2 cell fate decisions

+Selected Publications

  1. Miyabe C, Miyabe Y, Moreno L, Lian J, Rahimi RA, Miura NN, Ohno N, Iwakura Y, Kawakami T, Luster AD. Dectin-2-induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis. J Clin Invest. 2019 Jun 06; 130. PMID: 31169521.
  2. Rahimi RA, Luster AD. Chemokines: Critical Regulators of Memory T Cell Development, Maintenance, and Function. Adv Immunol. 2018; 138:71-98. PMID: 29731007.
  3. Lagares D, Santos A, Grasberger PE, Liu F, Probst CK, Rahimi RA, Sakai N, Kuehl T, Ryan J, Bhola P, Montero J, Kapoor M, Baron M, Varelas X, Tschumperlin DJ, Letai A, Tager AM. Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis. Sci Transl Med. 2017 Dec 13; 9(420). PMID: 29237758.
  4. Andrianifahanana M, Wilkes MC, Gupta SK, Rahimi RA, Repellin CE, Edens M, Wittenberger J, Yin X, Maidl E, Becker J, Leof EB. Profibrotic TGFß responses require the cooperative action of PDGF and ErbB receptor tyrosine kinases. FASEB J. 2013 Nov; 27(11):4444-54. PMID: 23913859.
  5. Rahimi RA, Skrzat J, Reddy DR, Zanni JM, Fan E, Stephens RS, Needham DM. Physical rehabilitation of patients in the intensive care unit requiring extracorporeal membrane oxygenation: a small case series. Phys Ther. 2013 Feb; 93(2):248-55. PMID: 23104895.
  6. Andrianifahanana M, Wilkes MC, Repellin CE, Edens M, Kottom TJ, Rahimi RA, Leof EB. ERBB receptor activation is required for profibrotic responses to transforming growth factor beta. Cancer Res. 2010 Oct 01; 70(19):7421-30. PMID: 20841477.
  7. Rahimi RA, Leof EB. TGFbeta versatility: PI3K as a critical mediator of distinct cell type and context specific responses. Cell Cycle. 2009 Jun 15; 8(12):1813-4. PMID: 19471120.
  8. Rahimi RA, Andrianifahanana M, Wilkes MC, Edens M, Kottom TJ, Blenis J, Leof EB. Distinct roles for mammalian target of rapamycin complexes in the fibroblast response to transforming growth factor-beta. Cancer Res. 2009 Jan 01; 69(1):84-93. PMID: 19117990.
  9. Rahimi RA, Allmond JJ, Wagner H, McCauley DW, Langeland JA. Lamprey snail highlights conserved and novel patterning roles in vertebrate embryos. Dev Genes Evol. 2009 Jan; 219(1):31-6. PMID: 18949485.
  10. Rahimi RA, Leof EB. TGF-beta signaling: a tale of two responses. J Cell Biochem. 2007 Oct 15; 102(3):593-608. PMID: 17729308.
  11. Wilke RA, Kolbert CP, Rahimi RA, Windebank AJ. Methylmercury induces apoptosis in cultured rat dorsal root ganglion neurons. Neurotoxicology. 2003 Jun; 24(3):369-78. PMID: 12782102.